SCSI vs. iSCSI -- features, functionality and architecture

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I am assuming you are asking about parallel or serial attached SCSI vs. iSCSI. iSCSI is the SCSI protocol mapped to TCP/IP and run over standard Ethernet technologies. This allows Ethernet networks to be deployed as SANs at a much lower TCO than Fibre Channel (FC).

Parallel SCSI and serial attached SCSI (SAS) are technologies designed to be inside a box such as DAS or within a storage array. They are not viable SAN technologies at this time.

The iSCSI on Ethernet (10/100/1000/10000) is a good viable external interconnect between application server initiators and storage targets. Parallel SCSI and SAS are good internal interconnects between the server and its internal storage or between the array controller and its drawers of hard disk drives (HDDs).